Protein Details: Aquaporin-1

Protein ID

ICDB_Pro_1744

Protein Name

Aquaporin-1

Gene Name

FgAQP1; FG00811; FGRAMPH1_01T02029

Organism

Gibberella zeae (strain ATCC MYA-4620 / CBS 123657 / FGSC 9075 / NRRL 31084 / PH-1) (Wheat head blight fungus) (Fusarium graminearum)

Length

318 amino acids

AlphaFoldDB

AF-V6QVS3-F1-model_v4.pdb

Function

Probable water channel involved in responses to changes in environmental conditions and conidiation . Involved in responses to hyperosmotic conditions; oxidative stress and cell wall destabilization . Also required for proper transcriptional activation of genes involved in aurofusarin biosynthesis . Not involved in pathogenicity; but negatively regulates deoxynivalenol (DON) production .

Sequence

MVQFGSRANTNMTGLPTEQAVEDRRVGNPKRDRMRNALVIVLGEFCGTFMFLLLSFIGAQTALVTNSPSDAGSPLLPFSLMYIAASFGTALAVNVWIFYRVSGGMFNPAVTLGLVLVGAVTPIHALLIIPTQLVAAITAAGITDALLPGKLLVTNALGNGTSVAQGVFIEMFLTSQLVLTVYFLAVEKHRSTHLAPIGIGISVFIAHICATNWTGTSINPARSFGPSVVAGFHGYDWIYYIGPFMGSLLAFGCYKIFKVLEYQTANPGQDDDNLDRSGHHHFFGHRKEPMPHTHTDNIEPKDHGVPQRNDSVIDDQMV

PDB Structures

Ligand Binding

1. DICL_CP

2. DICL_Pep

Binding Site

Disease

Location

DOI ID

10.1126/science.1143708; 10.1038/nature08850; 10.1186/s12864-015-1756-1; 10.1007/s00294-018-0818-8

RefSeq

XP_011316524.1